I am trying to print model for Prosthetic Hand (File Here: http://www.thingiverse.com/thing:596966) using Tinkerine 3D Printer. It went smooth for first hour and after that it started messing up(attached image). I checked the leveling of plate and it was fine. Also, the nozzle didn't get clogged anywhere. Can anyone suggest, what could be the reason for this or what should be inspected in order to overcome this?
The issue occurring here is similar to a question asked over here. It looks as though this is a result of a hardware fault related to the stepper drivers. @DarthPixel recommended placing heatsinks on the stepper driver(s) and/or properly placed fans.
Depending on the design of your machine, some stepper drivers are going to be worked harder than others. For example, a MakerBot Replicator will work the X-Axis stepper driver more than the Z-Axis stepper driver. Therefore, you have a higher chance of overheating your X-Axis stepper driver.(Images are of A4988 Stepper Driver, not directly compatible with MakerBot Replicator)
Alternatively, I personally have seen the issue repeated by manually triggering one of the limit switches. The effects seemed to take effect on the next layer.